
Great Plains Vacations from $364
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Your Great Plains Vacation
Leave the travel planning up to us with a Great Plains vacation package. With everything organized before you leave home, the only thing left for you to do is sit back, relax and experience this destination's culture and beauty. Your trip to Great Plains wouldn't be complete without experiencing some of its most well-known cities, starting with Houston. Two of the top attractions here include NRG Stadium and MD Anderson Cancer Center. Denver should also be on the itineraries of all Great Plains travelers. Visitors to this destination love Union Station and Empower Field at Mile High. Expedia has flights, hotels and everything else you need to help you curate your very own tailored Great Plains vacation today.
The Latest Great Plains vacation packages


The Shelborne By Proper, a Member of Design Hotels
Reviewed on Nov 16, 2025


Los Angeles Deluxe Suites - 2 Bedrooms & 2 Bathrooms
Reviewed on Nov 10, 2025

Cavalier Hotel South Beach
Reviewed on Nov 4, 2025
Where to stay in Great Plains

Downtown Denver
Dive into this bustling financial and entertainment hub, featuring the 16th Street pedestrian mall, Larimer Square, and the Theatre District. Catch a game at Coors Field or Ball Arena, and explore the neighborhood's vibrant dining scene.
Discover the most popular places to visit in Great Plains

Union Station
Combining transit, accommodations, shopping, dining, and events, this landmark building in downtown Denver offers history and excitement in the Mile High City.

Mount Rushmore
Explore the great outdoors at Mount Rushmore, a popular spot to commune with nature in Keystone. Discover the area's notable monuments, or seek out its horseback riding.

Garden of the Gods
Get a taste for the Colorado landscape as you explore this huge city park on your own or during a guided bus or Segway tour.
What to do in Great Plains

The Dinner Detective True Crime Murder Mystery Show - Wichita, KS
Great Plains Hotel Deals

Sonesta Denver Downtown
Room was clean and comfortable
Reviewed on Nov 14, 2025

Saskatoon Inn
Clean nice room, good bed
Reviewed on Nov 17, 2025

Spark by Hilton Denver International Airport
Great room and friendly staff!
Reviewed on Nov 18, 2025
























